Your back shouldn’t be the price of admission for seeing the world. If you’re planning multi-week adventures, the right backpack can turn airports, bus rides, and long walks into a surprisingly comfortable rhythm. We tested and researched the latest designs to find packs that carry heavy loads without torture. Read on to discover the 10 most comfortable travel backpacks of 2025—and which one fits your trip, body, and packing style.
Osprey Farpoint 55 / Fairview 55
The Osprey Farpoint 55 and Fairview 55 lead for long-trip comfort thanks to a backpacking-style suspension that genuinely supports weight. A plush, contoured hip belt and rigid frame transfer loads off your shoulders, making hours of transit feel manageable. Testers praised the breathable back panel that resists heat build-up in crowded terminals and humid climates. The detachable daypack adds daily flexibility, while the clamshell main compartment speeds packing at hostels and hotels. Durable fabrics and smart compression keep the bag balanced, even when fully loaded with cubes and shoes. Internal tie-downs and external grab points streamline transitions between trains, flights, and buses. For multi-week itineraries, this combo of comfort, access, and versatility is hard to beat.
Gregory Baltoro 65 / Deva 60
The Gregory Baltoro 65 and Deva 60 bring expedition-level support to extended travel. Their plush padding, dynamic FreeFloat suspension, and robust frames adapt to body movement, keeping heavy loads stable during long city walks or cross-country transit. Testers reported excellent load transfer that reduced shoulder fatigue and soreness. Organization is intuitive, with spacious compartments, quick-access pockets, and a supportive lid that doubles as practical storage. Ventilation helps on hot days, and durable materials withstand baggage handlers and bus racks alike. While not the lightest, comfort remains exceptional when carrying extra layers, shoes, or outdoor gear. For international backpackers and adventure travelers who pack heavy, the Baltoro/Deva delivers all-day comfort mile after mile.
Cotopaxi Allpa 42L Travel Pack
The Cotopaxi Allpa 42L excels for long trips where comfort meets urban durability. Its wide, supportive shoulder straps and structured body distribute weight evenly, preventing pressure points during airport dashes and long transfers. The TPU-coated shell shrugs off drizzle and rough handling, protecting tech and clothes. Testers loved the clamshell organization with mesh dividers, which keeps multi-destination packing tidy and fast. Even full, the Allpa stays balanced, aided by its firm frame sheet and well-placed grab handles. The included rain cover and theft-resistant zippers add security for buses and busy terminals. While hip belt padding is moderate, overall carry comfort is impressive for a 42L travel pack. It’s a superb pick for travelers juggling flights, buses, and walking-heavy days.
Osprey Aether Plus 60
The Osprey Aether Plus 60 stands out when your itinerary demands capacity and serious comfort. Its Fit-On-The-Fly adjustable hip belt and shoulder straps tailor fit on the go, while the LightWire frame keeps weight stable and off the shoulders. Testers praised breathability and endurance under heavy loads, noting less fatigue over long days. Generous volume means packing extra layers, boots, and gear for multi-climate trips without compromising balance. The lid and exterior lash points secure bulky items, and durable fabric resists scuffs from transport. Despite its size, access remains efficient with multiple entry points. For travelers blending city-to-trail adventures or extended international routes, the Aether Plus 60 delivers a custom-feeling, supportive carry.
Peak Design Travel Backpack 45L
The Peak Design Travel Backpack 45L pairs sleek efficiency with impressive comfort for long trips. Padded straps and a breathable back panel work with a structured frame to prevent sagging when fully loaded with clothes and tech. Testers appreciated quick side access, thoughtful cable and gadget organization, and durable weatherproof recycled materials. Its compressible design adapts to changing carry needs, while internal dividers and cube compatibility keep weight balanced. Although hip-belt padding is minimalist, the harness remains supportive for city-to-city travel. The clean exterior glides through overhead bins and security checkpoints. For digital nomads and travelers with tech-heavy loads, it delivers a refined, stable carry over extended journeys.
Deuter Aircontact Core 60+10
The Deuter Aircontact Core 60+10 continues to impress travelers who prioritize breathability and stability. Its Aircontact back system and supportive frame handle substantial loads while maintaining airflow during warm-weather journeys. The expandable collar adds capacity for souvenirs or extra layers, and the ergonomic hip belt improves comfort during long walks. Testers noted how planted and cool it felt in varied climates and transit scenarios. Durable fabrics resist abrasion, and access points simplify packing and retrieval. While it leans backpacking-first, the carry comfort translates perfectly to multi-week travel. For reliability across trains, buses, and foot travel, this pack delivers a consistently supportive ride.
Tortuga Travel Backpack 40L
The Tortuga 40L is crafted for long-term city-to-city travel with a harness that rivals many hiking packs. Thick shoulder padding, an adjustable torso, and a structured shell keep the load stable and comfortable through long walks and metro transfers. Testers praised the suitcase-style clamshell that simplifies packing and quick hotel turnover. Its thoughtful interior layout and laptop protection support digital nomads without sacrificing balance. The rectangular shape maximizes capacity yet avoids bulging that strains shoulders. While ventilation is modest, overall comfort remains high for extended travel days. If you prioritize carry-on compliance with true backpack comfort, the Tortuga 40L is a standout.
Patagonia Black Hole 32L (Long-Trip Minimalists)
The Patagonia Black Hole 32L delivers surprising comfort for minimalist long-trip travelers. Lightweight yet durable, its padded harness and streamlined frame carry daily essentials without hotspots. Testers noted all-day comfort when paired with packing cubes and ultralight wardrobes, especially for warm climates where bulk is unnecessary. The weatherproof fabric shrugs off rain and rough handling, while the simple interior keeps packing fast and focused. Though smaller than typical long-trip bags, it rewards disciplined packers with agility, easy overhead storage, and less fatigue. For ultralight itineraries and one-bag travel, it’s a reliable, comfortable companion.
REI Co-op Ruckpack 60
The REI Co-op Ruckpack 60 is purpose-built for travelers who balance hostels, buses, and long walks. Its load-friendly suspension, padded hip belt, and ventilated back panel reduce strain across full days. Testers appreciated the detachable daypack for city excursions and the tough exterior fabrics that handle overhead bins and bus racks. Organization is intuitive, with zip-away straps that protect the harness during check-in. Stability remains strong when packed to capacity, and the fit system accommodates a range of body types. For value-driven travelers who still demand comfort, the Ruckpack 60 checks all the boxes.
Thule Landmark 50L Men’s / 40L Women’s
The Thule Landmark line blends supportive carry with travel security that inspires confidence on international routes. Testers praised the breathable back panel and comfortable harness that stayed supportive during long stretches of sightseeing and transit. Lockable zippers and the SafeZone compartment protect valuables, while smart internal organization keeps weight centered. The men’s 50L and women’s 40L options offer size-appropriate fits without sacrificing features. Stability under full load impressed on stairs, cobblestones, and crowded terminals. For 2025’s long-distance travelers, it’s a compelling mix of comfort, protection, and organization.














